Freeze-drying of bioproducts: putting principles into practice.

نویسنده

  • F Franks
چکیده

The product and process parameters that determine successful freeze-drying are described and their interrelationships are explored. It is shown that the thermochemical and thermomechanical properties of water-soluble, amorphous materials form the basis of effective formulation design and that coordinated approaches to formulation and process development achieve optimum results with a minimum of trial-and-error experimentation.

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عنوان ژورنال:
  • European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V

دوره 45 3  شماره 

صفحات  -

تاریخ انتشار 1998